Managing MCAS

There is no one-size-fits-all treatment for Mast Cell Activation Syndrome (MCAS), but with the right tools and support, symptoms can often be managed and quality of life improved. Management usually includes a combination of self-care strategies and medical treatments.

Self-Management Stratagies

These day-to-day habits can help reduce flare-ups and empower patients to take control of their health:

Trigger Avoidance

Identify and avoid known triggers (foods, scents, heat, etc.)

Use fragrance-free, chemical-free products

Create a safe, low-stimulus environment

Diet & Nutrition

Follow a low-histamine diet

Keep a food/symptom diary to track reactions

Stay hydrated and avoid alcohol or processed foods

Stress Management

Practice calming techniques (Biblical Prayer, Deep Breathing)

Get regular sleep and maintain a routine

Seek emotional support through therapy or peer communities

Tracking & Planning

Use a symptom tracker app or journal

Prepare emergency plans for reactions

Educate friends, teachers, or employers about the condition

Medical Management

Always work with a healthcare provider who understands mast cell disorders. Medical treatment often includes:

Medications

Antihistamines (H1 and H2 blockers) – reduce histamine effects

Mast cell stabilizers (cromolyn sodium) – help prevent cell activation

Leukotriene inhibitors – control inflammation

Emergency medications (epinephrine) – for anaphylactic reactions

Testing & Diagnosis

May include tryptase levels, 24-hour urine testing, and response to treatment

MCAS is a clinical diagnosis — often based on symptoms and exclusion of other conditions

Long-Term Care

Involves regular monitoring and adjusting treatment as symptoms evolve

May include referrals to immunologists, gastroenterologists, or neurologists depending on symptom type

Take Note

Every MCAS patient is different. What works for one person may not work for another. It’s important to build a personalized care plan with a medical professional who listens and understands