Managing

Managing MCAS

There is no one-size-fits-all treatment for Mast Cell Activation Syndrome (MCAS), but with the right tools and support, symptoms can often be managed and quality of life improved. Management usually includes a combination of self-care strategies and medical treatments.

Self-Management Strategies

These day-to-day habits can help reduce flare-ups and empower patients to take control of their health:

Trigger Avoidance

Identify and avoid known triggers (foods, scents, heat, etc.)

Use fragrance-free, chemical-free products

Create a safe, low-stimulus environment

Diet & Nutrition

Follow a low-histamine diet

Keep a food/symptom diary to track reactions

Stay hydrated and avoid alcohol or processed foods

Stress Management

Practice calming techniques (meditation, deep breathing, gentle yoga)

Get regular sleep and maintain a routine

Seek emotional support through therapy or peer communities

Tracking & Planning

Use a symptom tracker app or journal

Prepare emergency plans for reactions

Educate friends, teachers, or employers about the condition

Medical Management

Always work with a healthcare provider who understands mast cell disorders. Medical treatment often includes:

Medications

Antihistamines (H1 and H2 blockers) – reduce histamine effects

Mast cell stabilizers (cromolyn sodium) – help prevent cell activation

Leukotriene inhibitors – control inflammation

Emergency medications (epinephrine) – for anaphylactic reactions

Testing & Diagnosis

May include tryptase levels, 24-hour urine testing, and response to treatment

MCAS is a clinical diagnosis — often based on symptoms and exclusion of other conditions

Long-Term Care

Involves regular monitoring and adjusting treatment as symptoms evolve

May include referrals to immunologists, gastroenterologists, or neurologists depending on symptom type

Take Note:

 Every MCAS patient is different. What works for one person may not work for another. It’s important to build a personalized care plan with a medical professional who listens and understands